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Bystolic is a prescription beta-adrenergic blocker containing nebivolol. It is approved for treatment of high blood pressure in adults and can be used alone or with other antihypertensive medicines. Tablets come in 2.5 mg, 5 mg, 10 mg, and 20 mg strengths. Most patients start with 5 mg once daily.
read more about bystolic ...The exact mechanism behind the blood pressure response to nebivolol is not definitively established. Proposed factors include reduced heart rate, lower heart muscle contractility, reduced sympathetic nerve activity, suppression of renin activity, vasodilation, and lower peripheral vascular resistance. Nebivolol has beta1-selective blocking activity at clinically relevant doses.
Bystolic is approved for hypertension in adults. Lowering blood pressure reduces cardiovascular risk over time, including risk of stroke and heart attack. Bystolic can be used by itself or with other antihypertensive medicines. Safety and efficacy in pediatric patients have not been established under current U.S. prescribing information.
Most adults start with 5 mg once daily, with or without food. The dose can increase at two-week intervals according to blood pressure response, up to 40 mg once daily. Patients with severe kidney impairment or moderate liver impairment start at 2.5 mg once daily. Bystolic is not recommended in severe liver impairment.
Bystolic should not be stopped abruptly in patients with coronary artery disease due risk of worsening angina, heart attack, or ventricular arrhythmias. Other concerns include slow heart rate, low blood pressure, heart block, worsening heart failure, bronchospasm, and masking of hypoglycemia symptoms. Severe bradycardia, advanced heart block, cardiogenic shock, decompensated heart failure, and severe liver impairment are contraindications.
Bystolic contains nebivolol, a beta-adrenergic blocker used to treat high blood pressure.
Bystolic is taken once daily, with or without food.
The hypertension dosing schedule permits increases up to 40 mg once daily.
No. Abrupt withdrawal can worsen angina or trigger serious cardiac events in people with coronary artery disease.
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DailyMed - BYSTOLIC (nebivolol) tablet. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=8b8ad213-1dc8-454e-a524-075685c0e1a8. Date Accessed September 18, 2026.
DailyMed - NEBIVOLOL tablet. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=51d3f12f-94cc-4f58-94d3-61990e16adfc. Date Accessed September 18, 2026.
Nebivolol. MedlinePlus. https://medlineplus.gov/druginfo/meds/a608029.html. Date Accessed September 18, 2026.
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