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Buspar is a trade name associated with buspirone hydrochloride, a prescription antianxiety medicine. Buspirone is used for management of anxiety disorders or short-term relief of anxiety symptoms. It is not a benzodiazepine and is not classified as a controlled substance. Current U.S. buspirone products are available in several oral strengths.
read more about buspar ...The exact mechanism of buspirone is unknown. Preclinical studies show high affinity for serotonin 5-HT1A receptors, where buspirone acts as a partial agonist. It also has activity involving dopamine receptors. Unlike benzodiazepines, buspirone does not have prominent anticonvulsant or muscle-relaxant activity and has less prominent sedative activity.
Buspirone is indicated for management of anxiety disorders or short-term relief of anxiety symptoms. Clinical trials supporting its use enrolled patients whose symptoms corresponded to generalized anxiety disorder. Anxiety or tension tied to ordinary daily stress does not usually require treatment with an anxiolytic medicine.
Buspirone treatment starts at 15 mg daily, commonly as 7.5 mg twice daily. The dose can increase by 5 mg per day at intervals of two to three days. The maximum daily dose is 60 mg. Patients take buspirone consistently in relation to food, either with food each time or without food each time.
Buspirone can cause dizziness, nausea, headache, nervousness, lightheadedness, and excitement. Serotonin syndrome can occur, especially with serotonergic medicines or monoamine oxidase inhibitors. Use with an MAOI used for depression, or within 14 days of one, is contraindicated. Buspirone is not recommended in severe liver or kidney impairment due increased drug exposure.
No. Buspirone is chemically and pharmacologically different from benzodiazepines and is not a controlled substance.
Buspirone is used for management of anxiety disorders or short-term relief of anxiety symptoms.
Starting treatment commonly uses 7.5 mg twice daily, with later dose changes based on clinical response.
Yes. Buspirone should be taken consistently in relation to food, either with food each time or without food each time.
BuSpar (buspirone hydrochloride) Prescribing Information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/018731s051lbl.pdf. Date Accessed September 18, 2026.
Buspirone. MedlinePlus. https://medlineplus.gov/druginfo/meds/a688005.html. Date Accessed September 18, 2026.
Buspirone. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK531477/. Date Accessed September 18, 2026.
DailyMed - BUSPIRONE HYDROCHLORIDE tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=75b1ae3f-e926-4555-a0e9-50323fc66cb2. Date Accessed September 18, 2026.
DailyMed - BUSPIRONE HYDROCHLORIDE tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=801803eb-be17-4064-8813-7ccf52316cde. Date Accessed September 18, 2026.