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Bumex is a prescription oral product containing bumetanide, a potent loop diuretic. It is used for edema associated with congestive heart failure, liver disease, kidney disease, and nephrotic syndrome. Bumex tablets come in 0.5 mg, 1 mg, and 2 mg strengths. The dose is individualized according to fluid status, response, and electrolyte changes.
read more about bumex ...Bumetanide acts mainly in the ascending limb of the loop of Henle and inhibits sodium reabsorption. Chloride reabsorption is also blocked, while potassium excretion increases. The resulting rise in urinary salt and water loss reduces fluid accumulation. After an oral dose, diuresis begins within about 30 to 60 minutes and is relatively short acting.
Bumex tablets are indicated for edema associated with congestive heart failure, hepatic disease, renal disease, and nephrotic syndrome. Oral treatment is used when gastrointestinal absorption is adequate. The medicine is contraindicated in anuria, hepatic coma, severe electrolyte depletion that has not been corrected, and hypersensitivity to bumetanide.
The usual total daily dose is 0.5 mg to 2 mg and is commonly taken as one dose. When the initial response is inadequate, a second or third dose can be given at four- to five-hour intervals. The maximum labeled daily dose is 10 mg. Patients with hepatic failure receive the lowest practical dose.
Bumex carries a boxed warning for profound diuresis with water and electrolyte depletion. Excessive dosing can cause dehydration, low blood volume, low potassium, circulatory collapse, thrombosis, and worsening kidney function. Hearing impairment and severe skin reactions have also been reported. Fluid status, kidney function, and serum electrolytes require clinical monitoring during treatment.
Yes. Bumex tablets contain bumetanide, a loop diuretic used for selected forms of edema.
Diuresis generally begins within 30 to 60 minutes after an oral dose.
Bumex tablets come in 0.5 mg, 1 mg, and 2 mg strengths.
Yes. The boxed warning concerns profound water and electrolyte depletion from excessive diuresis.
BUMEX (bumetanide) Tablets Prescribing Information. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/018225Orig1s029lbl.pdf. Date Accessed September 18, 2026.
Bumetanide. MedlinePlus. https://www.medlineplus.gov/druginfo/meds/a684051.html. Date Accessed September 18, 2026.
Bumetanide. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK559181/. Date Accessed September 18, 2026.
DailyMed - BUMETANIDE tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=06745425-e7e7-4413-b9ff-22b121f0ea9a. Date Accessed September 18, 2026.
DailyMed - BUMEX (bumetanide) tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=32dfbea3-eb2b-4070-8605-57ce3e6d5a2f. Date Accessed September 18, 2026.