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Azelastine is an antihistamine with histamine H1 receptor antagonist activity. Prescription forms include a 0.1 percent nasal spray for seasonal allergic rhinitis and vasomotor rhinitis and 0.05 percent eye drops for itching associated with allergic conjunctivitis. Age limits and dosing differ by formulation, so the instructions for the exact product guide use.
read more about azelastine ...Azelastine blocks histamine H1 receptors. Histamine is one of the mediators involved in allergic symptoms such as sneezing, nasal itching, runny nose, and itchy eyes. Azelastine also has activity involving other mediators released during allergic responses. Its local nasal and ophthalmic forms act at the sites where allergy symptoms occur.
Azelastine 0.1 percent nasal spray treats seasonal allergic rhinitis in patients age 5 and older and vasomotor rhinitis in patients age 12 and older. Azelastine 0.05 percent eye drops treat itching associated with allergic conjunctivitis. The eye drops are not intended for irritation caused by contact lens wear.
For seasonal allergic rhinitis, patients age 12 and older use one or two nasal sprays per nostril twice daily, while ages 5 to 11 use one spray per nostril twice daily. Vasomotor rhinitis uses two sprays per nostril twice daily for ages 12 and older. Eye drops are instilled as one drop in each affected eye twice daily.
Nasal azelastine can cause bitter taste, headache, sleepiness, nasal burning, dry mouth, dizziness, and nosebleeds. Alcohol and other central nervous system depressants can worsen drowsiness and reduced alertness. Azelastine eye drops can cause temporary eye irritation. The dropper tip should not touch the eye, eyelids, or nearby surfaces.
Yes. Azelastine is a histamine H1 receptor antagonist used in nasal spray and eye drop formulations.
The 0.1 percent nasal spray treats seasonal allergic rhinitis and vasomotor rhinitis under labeled age criteria.
Azelastine 0.05 percent eye drops treat itching associated with allergic conjunctivitis.
Yes. Sleepiness has been reported with nasal azelastine, and alcohol or sedating medicines can worsen reduced alertness.
Azelastine Nasal Spray. MedlinePlus. https://medlineplus.gov/druginfo/meds/a697014.html. Date Accessed September 15, 2026.
Azelastine Ophthalmic. MedlinePlus. https://medlineplus.gov/druginfo/meds/a603009.html. Date Accessed September 15, 2026.
DailyMed - AZELASTINE HYDROCHLORIDE nasal spray, 0.1%. https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bca75501-4140-4d77-e053-2a95a90a019f. Date Accessed September 15, 2026.
DailyMed - AZELASTINE HYDROCHLORIDE ophthalmic solution, 0.05%. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6945fb86-27fb-4bab-8908-98772c6269c5. Date Accessed September 15, 2026.
DailyMed - AZELASTINE HYDROCHLORIDE nasal spray, Amneal Pharmaceuticals. https://www.dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=7902605c-944a-4d7e-a7d4-eb4a71bcacdb&type=display. Date Accessed September 15, 2026.