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What Is Auvi-Q?

Auvi-Q is a single-dose epinephrine autoinjector used for emergency treatment of type I allergic reactions, including anaphylaxis. It is approved for adults and children who weigh at least 7.5 kg. Auvi-Q comes in 0.1 mg, 0.15 mg, and 0.3 mg strengths and includes electronic voice instructions, audible signals, and visual cues during use.

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What Is Auvi-Q?

Auvi-Q is a single-dose epinephrine autoinjector used for emergency treatment of type I allergic reactions, including anaphylaxis. It is approved for adults and children who weigh at least 7.5 kg. Auvi-Q comes in 0.1 mg, 0.15 mg, and 0.3 mg strengths and includes electronic voice instructions, audible signals, and visual cues during use.

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How Does Auvi-Q Reverse Anaphylaxis?

Epinephrine stimulates alpha and beta adrenergic receptors. Alpha receptor activity constricts blood vessels and raises vascular resistance, which counters low blood pressure and swelling. Beta receptor activity increases cardiac activity and relaxes bronchial smooth muscle, helping open narrowed airways during anaphylaxis. Epinephrine also reduces release of allergic mediators from mast cells.

How Is the Correct Auvi-Q Dose Selected?

Auvi-Q dosing is based on body weight. Patients weighing 30 kg or more use 0.3 mg. Those weighing 15 kg to less than 30 kg use 0.15 mg, and those weighing 7.5 kg to less than 15 kg use 0.1 mg. The device is injected into the outer thigh, through clothing when necessary.

When Can a Second Auvi-Q Dose Be Used?

If symptoms do not improve or become worse after the first injection, a second dose from a second autoinjector can be given starting five minutes after the first dose. Patients are advised to have immediate access to two devices and seek emergency medical care after treatment for continued observation and further care when needed.

What Safety Precautions Apply to Auvi-Q?

Auvi-Q should not be injected into a vein, buttock, fingers, hands, or feet. Accidental injection into a digit can reduce blood flow. Epinephrine can cause palpitations, tremor, anxiety, dizziness, headache, nausea, and heart rhythm problems. Young children should have the leg held firmly during injection to reduce injection-related injury.

Frequently Asked Questions About Auvi-Q

Is Auvi-Q used for anaphylaxis?

Yes. Auvi-Q is used for emergency treatment of type I allergic reactions, including anaphylaxis.

Where is Auvi-Q injected?

Auvi-Q is injected into the outer thigh and can be given through clothing when necessary.

What strengths does Auvi-Q come in?

Auvi-Q comes in 0.1 mg, 0.15 mg, and 0.3 mg strengths selected according to body weight.

Can a second Auvi-Q dose be given?

Yes. A second autoinjector can be used starting five minutes after the first dose when symptoms do not improve or become worse.

References

AUVI-Q Instructions for Use. https://www.auvi-q.com/pdf/Patient-Information.pdf. Date Accessed September 14, 2026.

AUVI-Q Training and Resources. https://www.auvi-q.com/public-access/auvi-q-training-resources. Date Accessed September 14, 2026.

DailyMed - AUVI-Q (epinephrine) injection, solution. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6180fb40-7fca-4602-b3da-ce62b8cd2470. Date Accessed September 14, 2026.

Epinephrine. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK482160/. Date Accessed September 14, 2026.

Epinephrine Injection. MedlinePlus. https://medlineplus.gov/druginfo/meds/a603002.html. Date Accessed September 14, 2026.