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Arimidex is a prescription medicine containing anastrozole, an aromatase inhibitor. It is approved for postmenopausal women with selected hormone-sensitive breast cancers. Uses include adjuvant treatment of hormone receptor-positive early breast cancer, first-line treatment of hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic disease, and advanced breast cancer that progresses after tamoxifen therapy.
read more about arimidex ...Anastrozole inhibits aromatase, the enzyme that converts adrenal androgens into estrogens in peripheral tissues after menopause. Lower estrogen concentrations reduce hormonal stimulation of breast cancer cells that depend on estrogen signaling. Arimidex does not have progestogenic, androgenic, or estrogenic activity at therapeutic doses.
Arimidex is used in postmenopausal women with hormone receptor-positive early breast cancer after initial treatment. It is also approved as first-line therapy for hormone receptor-positive or receptor-unknown locally advanced or metastatic breast cancer and for advanced disease that progresses after tamoxifen treatment.
The recommended dose is one 1 mg tablet by mouth once daily, with or without food. For advanced breast cancer, treatment continues until tumor progression. No dose adjustment is required for kidney impairment or mild to moderate liver impairment. Arimidex has not been studied in severe liver impairment.
Arimidex can reduce bone mineral density and raise fracture risk. Other concerns include higher cholesterol and ischemic cardiovascular events in women with pre-existing ischemic heart disease. The medicine can harm a fetus. Common reactions include hot flashes, joint symptoms, weakness, depression, nausea, headache, osteoporosis, and back pain.
Yes. Arimidex contains anastrozole, an aromatase inhibitor used for selected breast cancers in postmenopausal women.
The labeled dose is one 1 mg tablet by mouth once daily, with or without food.
Yes. Lower estrogen concentrations during treatment can reduce bone mineral density and raise fracture risk.
No. Tamoxifen should not be taken with Arimidex since it lowers anastrozole blood concentrations and therapeutic activity.
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Anastrozole. National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/drugs/anastrozole. Date Accessed September 14, 2026.
ARIMIDEX (anastrozole) Prescribing Information. https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=acbfaaa9-503c-4691-9828-76a7146ed6de&type=pdf. Date Accessed September 14, 2026.
DailyMed - ARIMIDEX (anastrozole) tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acbfaaa9-503c-4691-9828-76a7146ed6de. Date Accessed September 14, 2026.
FDALabel - ARIMIDEX (anastrozole). https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/388033. Date Accessed September 14, 2026.