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Aptiom is a prescription antiseizure medicine containing eslicarbazepine acetate. It is approved for partial-onset seizures in patients age 4 and older and can be used alone or with other antiseizure medicines. Tablets come in 200 mg, 400 mg, 600 mg, and 800 mg strengths and are taken once daily.
read more about aptiom ...Eslicarbazepine acetate is converted extensively to eslicarbazepine after dosing. The exact anticonvulsant mechanism is not known, but eslicarbazepine is thought to inhibit voltage-gated sodium channels. Reducing sodium channel activity can limit repetitive firing of neurons involved in partial-onset seizures.
Aptiom is approved for partial-onset seizures in adults and children age 4 and older. It can be used as monotherapy or together with other antiseizure medicines. Pediatric dosing is based on body weight. Safety and efficacy have not been established for children younger than 4.
Adults commonly start at 400 mg once daily and increase at weekly intervals to a maintenance dose of 800 mg to 1600 mg once daily. Pediatric dosing is weight based. Moderate or severe kidney impairment requires a 50 percent dose reduction. Tablets can be swallowed whole or crushed and taken with or without food.
Serious risks include suicidal thoughts or behavior, severe skin reactions, DRESS, anaphylaxis, angioedema, low blood sodium, neurologic problems, liver injury, and blood disorders. Dizziness, sleepiness, nausea, headache, double vision, vomiting, fatigue, vertigo, poor coordination, blurred vision, and tremor are common. Aptiom is withdrawn gradually to reduce increased seizure frequency and status epilepticus risk.
Yes. Aptiom is approved for partial-onset seizures in patients age 4 and older.
Aptiom is taken once daily. Adult and pediatric doses differ according to age, weight, kidney function, response, and tolerability.
Yes. Current labeling states that Aptiom tablets can be taken whole or crushed.
No. The dose is reduced gradually to lower the risk of increased seizure frequency and status epilepticus.
APTIOM (eslicarbazepine acetate) Prescribing Information. https://www.aptiom.com/Aptiom-Prescribing-Information.pdf. Date Accessed September 14, 2026.
DailyMed - APTIOM (eslicarbazepine acetate) tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3d0c9554-eaeb-4694-8089-00133fcadce3. Date Accessed September 14, 2026.
DailyMed - ESLICARBAZEPINE ACETATE tablet. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2067fb77-9657-44da-b430-02e8a4efacb5. Date Accessed September 14, 2026.
Eslicarbazepine. MedlinePlus. https://medlineplus.gov/druginfo/meds/a614032.html. Date Accessed September 14, 2026.
FDA Label - APTIOM (eslicarbazepine acetate) Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/022416Orig1s021lbl.pdf. Date Accessed September 14, 2026.