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Alfuzosin is a prescription alpha1-adrenergic blocker used to treat signs and symptoms of benign prostatic hyperplasia (BPH) in adult men. It relaxes smooth muscle in the prostate and bladder neck, which improves urine flow and reduces urinary symptoms. Extended-release alfuzosin tablets contain 10 mg and are taken once daily with food at the same meal each day.
read more about alfuzosin ...Alfuzosin blocks postsynaptic alpha1-adrenergic receptors in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra. Blocking these receptors relaxes smooth muscle in the lower urinary tract. This decreases resistance to urine flow and reduces BPH symptoms such as weak stream, difficulty starting urination, and incomplete bladder emptying.
Alfuzosin extended-release tablets are approved for adult men with signs and symptoms of benign prostatic hyperplasia. The medicine is not approved to treat high blood pressure and is not indicated for pediatric patients. A clinician also considers other causes of urinary symptoms, including prostate cancer, before or during treatment.
The recommended dose is one 10 mg extended-release tablet once daily with food and with the same meal each day. Taking alfuzosin without food lowers drug absorption. Tablets are swallowed whole and should not be crushed or chewed. The medicine is contraindicated with potent CYP3A4 inhibitors and in people with moderate or severe liver impairment.
Alfuzosin can cause postural low blood pressure, dizziness, and fainting, especially when treatment begins or when used with blood pressure medicines or nitrates. Other concerns include QT prolongation, worsening angina, and intraoperative floppy iris syndrome during cataract surgery. Caution is needed with severe kidney impairment and mild liver impairment.
Yes. Alfuzosin treats urinary signs and symptoms associated with benign prostatic hyperplasia in adult men.
Alfuzosin can lower blood pressure, but it is not approved as a treatment for hypertension.
Yes. The extended-release tablet is taken with food and with the same meal each day.
No. Extended-release alfuzosin tablets should be swallowed whole and should not be crushed or chewed.
Alfuzosin. MedlinePlus. https://medlineplus.gov/druginfo/meds/a604002.html. Date Accessed September 11, 2026.
Alpha-Blockers. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK556066/. Date Accessed September 11, 2026.
DailyMed - ALFUZOSIN HYDROCHLORIDE tablet, extended release. https://www.dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=26fcc267-c8d7-e059-1bcf-830dded43690&type=display. Date Accessed September 11, 2026.
DailyMed - UROXATRAL (alfuzosin HCl) tablet, extended release. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9fc7f119-f36b-44cf-945d-940160f3afe3. Date Accessed September 11, 2026.
UROXATRAL (alfuzosin hydrochloride) 10 mg Extended-Release Tablets Approval. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/21-287_Uroxatral_Approv.pdf. Date Accessed September 11, 2026.